Miss Jennifer Cassels

  • Technician (Paul O'Gorman Leukaemia Research Centre)

telephone: 01413308124
email: Jennifer.Cassels@glasgow.ac.uk

Paul O'Gorman Leukaemia Res Cent, Gartnavel General Hospital, 21 Shelly Road Glasgow G12 0XB

Import to contacts

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2022 | 2020 | 2019 | 2017 | 2016 | 2013
Number of items: 14.

2025

Omar, R. et al. (2025) The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome. Cell Death Discovery, 11(1), 200. (doi: 10.1038/s41420-025-02476-y) (PMID:40280907) (PMCID:PMC12032211)

2024

Laing, A. et al. (2024) Paediatric bone marrow mesenchymal stem cells support acute myeloid leukaemia cell survival and enhance chemoresistance via contact-independent mechanism. British Journal of Haematology, (doi: 10.1111/bjh.19884) (Early Online Publication)

Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0)

2023

Malik, Natasha ORCID logoORCID: https://orcid.org/0000-0002-1768-3544, Hay, Jodie ORCID logoORCID: https://orcid.org/0000-0002-2000-2578, Almuhanna, Hassan N.B., Dunn, Karen M., Lees, Jamie, Cassels, Jennifer, Li, Jiatian, Nakagawa, Rinako, Sansom, Owen J. ORCID logoORCID: https://orcid.org/0000-0001-9540-3010 and Michie, Alison M. ORCID logoORCID: https://orcid.org/0000-0002-5404-475X (2023) mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia. Leukemia, 37, pp. 2414-2425. (doi: 10.1038/s41375-023-02043-3) (PMID:37775560) (PMCID:PMC10681897)

2022

Hay, J. et al. (2022) PKCβ facilitates leukemogenesis in chronic lymphocytic leukaemia by promoting constitutive BCR-mediated signalling. Cancers, 14(23), 6006. (doi: 10.3390/cancers14236006) (PMID:36497487) (PMCID:PMC9735720)

Parry, Narissa, Busch, Caroline, Aßmann, Victoria, Cassels, Jennifer, Hair, Alan, Helgason, G. Vignir ORCID logoORCID: https://orcid.org/0000-0003-1616-132X, Wheadon, Helen ORCID logoORCID: https://orcid.org/0000-0001-9902-3170 and Copland, Mhairi ORCID logoORCID: https://orcid.org/0000-0002-7655-016X (2022) BH3 mimetics in combination with nilotinib or ponatinib represent a promising therapeutic strategy in blast phase chronic myeloid leukemia. Cell Death Discovery, 8, 457. (doi: 10.1038/s41420-022-01211-1) (PMID:36379918) (PMCID:PMC9666353)

2020

Kinstrie, R. et al. (2020) CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy. Leukemia, 34(6), pp. 1613-1625. (doi: 10.1038/s41375-019-0684-5) (PMID:31896780) (PMCID:PMC7272220)

2019

Malik, Natasha ORCID logoORCID: https://orcid.org/0000-0002-1768-3544, Dunn, Karen M., Cassels, Jennifer, Hay, Jodie ORCID logoORCID: https://orcid.org/0000-0002-2000-2578, Estell, Christopher, Sansom, Owen J. ORCID logoORCID: https://orcid.org/0000-0001-9540-3010 and Michie, Alison M. ORCID logoORCID: https://orcid.org/0000-0002-5404-475X (2019) mTORC1 activity is essential for erythropoiesis and B cell lineage commitment. Scientific Reports, 9, 16917. (doi: 10.1038/s41598-019-53141-1) (PMID:31729420) (PMCID:PMC6858379)

Hay, Jodie ORCID logoORCID: https://orcid.org/0000-0002-2000-2578, Moles, Michael W., Cassels, Jennifer and Michie, Alison M. ORCID logoORCID: https://orcid.org/0000-0002-5404-475X (2019) Subcellular fractionation of primary chronic lymphocytic leukemia cells to monitor nuclear/ cytoplasmic protein trafficking. Journal of Visualized Experiments(152), e60426. (doi: 10.3791/60426) (PMID:31710039)

2017

Tarafdar, A. et al. (2017) CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression. Blood, 129(2), pp. 199-208. (doi: 10.1182/blood-2016-09-742049) (PMID:27793879) (PMCID:PMC5305055)

2016

Horne, Gillian A. ORCID logoORCID: https://orcid.org/0000-0001-9741-7352, Morrison, Heather, Campbell, Victoria, Kinstrie, Ross, Cassels, Jennifer, Hair, Alan, Vetrie, David ORCID logoORCID: https://orcid.org/0000-0003-2075-4662, Wheadon, Helen ORCID logoORCID: https://orcid.org/0000-0001-9902-3170, Holyoake, Tessa L. and Copland, Mhairi ORCID logoORCID: https://orcid.org/0000-0002-7655-016X (2016) Notch Pathway Activation Targets Leukemic Stem Cells in Chronic-Phase Chronic Myeloid Leukemia (CP-CML). American Society of Hematology 58th Annual Meeting, San Diego, CA, USA, 3-6 Dec 2016.

Scott, M. T. et al. (2016) Epigenetic reprogramming sensitizes CML stem cells to combined EZH2 and tyrosine kinase inhibition. Cancer Discovery, 6(11), pp. 1248-1257. (doi: 10.1158/2159-8290.CD-16-0263) (PMID:27630125) (PMCID:PMC6538532)

Michie, A.M. ORCID logoORCID: https://orcid.org/0000-0002-5404-475X, Tarafdar, A., Gallipoli, P., Pellicano, F., Hopcroft, L. ORCID logoORCID: https://orcid.org/0000-0002-7022-1322, Korfi, K., Cassels, J., Jorgensen, H.J. ORCID logoORCID: https://orcid.org/0000-0003-4663-4191, Vetrie, D. ORCID logoORCID: https://orcid.org/0000-0003-2075-4662 and Holyoake, T.L. (2016) CML Cells Actively Evade Host Immune Surveillance Through Cytokine-Mediated Downregulation of MHC-I I Expression. 36th World Congress of the International Society of Hematology, Glasgow, Scotland, 18-21 Apr 2016. p. 117. (doi: 10.1111/bjh.14019)

2013

Abraham, Sheela, Hopcroft, Lisa ORCID logoORCID: https://orcid.org/0000-0002-7022-1322, Carrick, Emma, Williamson, Andrew, Pierce, Andrew, Cassels, Jennifer, Pellicano, Francesca, Whetton, Anthony and Holyoake, Tessa L. (2013) p53 and c-Myc are critical signaling hubs that maintain chronic myeloid leukemia. In: 55th American Society of Hematology Annual Meeting and Exposition, New Orleans, LA, USA, 7-10 Dec 2013, p. 1465.

This list was generated on Mon Jul 7 16:49:27 2025 BST.
Jump to: Articles | Conference or Workshop Item | Conference Proceedings
Number of items: 14.

Articles

Omar, R. et al. (2025) The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome. Cell Death Discovery, 11(1), 200. (doi: 10.1038/s41420-025-02476-y) (PMID:40280907) (PMCID:PMC12032211)

Laing, A. et al. (2024) Paediatric bone marrow mesenchymal stem cells support acute myeloid leukaemia cell survival and enhance chemoresistance via contact-independent mechanism. British Journal of Haematology, (doi: 10.1111/bjh.19884) (Early Online Publication)

Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0)

Malik, Natasha ORCID logoORCID: https://orcid.org/0000-0002-1768-3544, Hay, Jodie ORCID logoORCID: https://orcid.org/0000-0002-2000-2578, Almuhanna, Hassan N.B., Dunn, Karen M., Lees, Jamie, Cassels, Jennifer, Li, Jiatian, Nakagawa, Rinako, Sansom, Owen J. ORCID logoORCID: https://orcid.org/0000-0001-9540-3010 and Michie, Alison M. ORCID logoORCID: https://orcid.org/0000-0002-5404-475X (2023) mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia. Leukemia, 37, pp. 2414-2425. (doi: 10.1038/s41375-023-02043-3) (PMID:37775560) (PMCID:PMC10681897)

Hay, J. et al. (2022) PKCβ facilitates leukemogenesis in chronic lymphocytic leukaemia by promoting constitutive BCR-mediated signalling. Cancers, 14(23), 6006. (doi: 10.3390/cancers14236006) (PMID:36497487) (PMCID:PMC9735720)

Parry, Narissa, Busch, Caroline, Aßmann, Victoria, Cassels, Jennifer, Hair, Alan, Helgason, G. Vignir ORCID logoORCID: https://orcid.org/0000-0003-1616-132X, Wheadon, Helen ORCID logoORCID: https://orcid.org/0000-0001-9902-3170 and Copland, Mhairi ORCID logoORCID: https://orcid.org/0000-0002-7655-016X (2022) BH3 mimetics in combination with nilotinib or ponatinib represent a promising therapeutic strategy in blast phase chronic myeloid leukemia. Cell Death Discovery, 8, 457. (doi: 10.1038/s41420-022-01211-1) (PMID:36379918) (PMCID:PMC9666353)

Kinstrie, R. et al. (2020) CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy. Leukemia, 34(6), pp. 1613-1625. (doi: 10.1038/s41375-019-0684-5) (PMID:31896780) (PMCID:PMC7272220)

Malik, Natasha ORCID logoORCID: https://orcid.org/0000-0002-1768-3544, Dunn, Karen M., Cassels, Jennifer, Hay, Jodie ORCID logoORCID: https://orcid.org/0000-0002-2000-2578, Estell, Christopher, Sansom, Owen J. ORCID logoORCID: https://orcid.org/0000-0001-9540-3010 and Michie, Alison M. ORCID logoORCID: https://orcid.org/0000-0002-5404-475X (2019) mTORC1 activity is essential for erythropoiesis and B cell lineage commitment. Scientific Reports, 9, 16917. (doi: 10.1038/s41598-019-53141-1) (PMID:31729420) (PMCID:PMC6858379)

Hay, Jodie ORCID logoORCID: https://orcid.org/0000-0002-2000-2578, Moles, Michael W., Cassels, Jennifer and Michie, Alison M. ORCID logoORCID: https://orcid.org/0000-0002-5404-475X (2019) Subcellular fractionation of primary chronic lymphocytic leukemia cells to monitor nuclear/ cytoplasmic protein trafficking. Journal of Visualized Experiments(152), e60426. (doi: 10.3791/60426) (PMID:31710039)

Tarafdar, A. et al. (2017) CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression. Blood, 129(2), pp. 199-208. (doi: 10.1182/blood-2016-09-742049) (PMID:27793879) (PMCID:PMC5305055)

Scott, M. T. et al. (2016) Epigenetic reprogramming sensitizes CML stem cells to combined EZH2 and tyrosine kinase inhibition. Cancer Discovery, 6(11), pp. 1248-1257. (doi: 10.1158/2159-8290.CD-16-0263) (PMID:27630125) (PMCID:PMC6538532)

Conference or Workshop Item

Horne, Gillian A. ORCID logoORCID: https://orcid.org/0000-0001-9741-7352, Morrison, Heather, Campbell, Victoria, Kinstrie, Ross, Cassels, Jennifer, Hair, Alan, Vetrie, David ORCID logoORCID: https://orcid.org/0000-0003-2075-4662, Wheadon, Helen ORCID logoORCID: https://orcid.org/0000-0001-9902-3170, Holyoake, Tessa L. and Copland, Mhairi ORCID logoORCID: https://orcid.org/0000-0002-7655-016X (2016) Notch Pathway Activation Targets Leukemic Stem Cells in Chronic-Phase Chronic Myeloid Leukemia (CP-CML). American Society of Hematology 58th Annual Meeting, San Diego, CA, USA, 3-6 Dec 2016.

Michie, A.M. ORCID logoORCID: https://orcid.org/0000-0002-5404-475X, Tarafdar, A., Gallipoli, P., Pellicano, F., Hopcroft, L. ORCID logoORCID: https://orcid.org/0000-0002-7022-1322, Korfi, K., Cassels, J., Jorgensen, H.J. ORCID logoORCID: https://orcid.org/0000-0003-4663-4191, Vetrie, D. ORCID logoORCID: https://orcid.org/0000-0003-2075-4662 and Holyoake, T.L. (2016) CML Cells Actively Evade Host Immune Surveillance Through Cytokine-Mediated Downregulation of MHC-I I Expression. 36th World Congress of the International Society of Hematology, Glasgow, Scotland, 18-21 Apr 2016. p. 117. (doi: 10.1111/bjh.14019)

Conference Proceedings

Abraham, Sheela, Hopcroft, Lisa ORCID logoORCID: https://orcid.org/0000-0002-7022-1322, Carrick, Emma, Williamson, Andrew, Pierce, Andrew, Cassels, Jennifer, Pellicano, Francesca, Whetton, Anthony and Holyoake, Tessa L. (2013) p53 and c-Myc are critical signaling hubs that maintain chronic myeloid leukemia. In: 55th American Society of Hematology Annual Meeting and Exposition, New Orleans, LA, USA, 7-10 Dec 2013, p. 1465.

This list was generated on Mon Jul 7 16:49:27 2025 BST.