Professor Huabing Yin
- Professor of Biomedical Engineering (Biomedical Engineering)
telephone:
+44(0)1413304109
email:
Huabing.Yin@glasgow.ac.uk
Room 626, Rankine Building, Oakfield Avenue, Glasgow G12 8LT
Biography
Professor Huabing Yin is the Head of the Biomedical Engineering Division at the James Watt School of Engineering, University of Glasgow. She was awarded a personal research fellowship from the Royal Society of Edinburgh (2006-2009) and was promoted to Professor in 2017.
Prior to joining the University of Glasgow, she worked as a postdoctoral researcher at the University of Southampton (2003-2005) after receiving her PhD in Chemical Engineering from Swansea University, UK, in 2002.
Professor Yin’s vision is to develop innovative technologies to address major healthcare and global challenges, with a particular focus on antibiotic resistance, medical diagnosis and environmental sustainably. She has extensive expertise in microfluidics and is a pioneer in the development of Raman-activated cell sorting technologies. These technologies enable the investigations of biological systems at the single-cell level, offering disruptive solutions to long-standing challenges. One recent example is her team’s integrated microfluidic platform combined with Raman spectroscopy for culture-free diagnosis of microbial infections within minutes, addressing a vital challenge posed by life-threatening antimicrobial resistance (Nature Communications Paper).
She has published over 125 papers in peer-reviewed journals (including Nature Communications, Advanced Materials, and ACS Nano), including eight highly cited papers in Web of Science, and has an H-index of 47 (Google Scholar). She regularly serves as panel members for UKRI and European Union research foundations.
Research interests
Research Interests
Most of our research is interdisciplinary, integrating advancement in microfluidics, optical technologies, nanotechnology and artificial intelligence.
Single-cell analysis and Raman activated cell sorting:
Even within genetically identical populations, individual cells can differ markedly. This cellular heterogeneity can profoundly influence cell fate but is often masked by traditional population-averaged approaches. Our group have developed novel methods and devices to analyse single cells within populations across both mammalian systems and microorganisms. These innovations have demonstrated significant potential in addressing challenges in environmental microbiology, antibiotic resistance, synthetic biology and cancer research.
Engineering cellular microenvironments:
The interaction between a cell and its environment is governed by a broad spectrum of physical, chemical and biological cues. We integrate microfluidic technologies with sensors and biomaterials to develop organ-on-a-chip platforms and 3D engineered tissue constructs that resemble key features in the naturally occurring microenvironments. In collaboration with life scientists and pharmaceutical industry, we are implementing these devices for drug screening and tissue regeneration.
Atomic Force Microscopy (AFM) and Nanoscale thermal biology:
The physical and mechanical properties of cells and tissues contain intrinsic information related to their physiological and pathological status. We have developed a range of AFM-based methods to quantify cell mechanical properties (e.g. stiffness, viscoelasticity) and cell–matrix interactions, advancing understanding of cancer development and progression. More recently, in collaboration with Dr Phil Dobson and Prof John Weaver, we have developed innovative aqueous Scanning thermal microscopy technologies, enabling the probing of heat and temperature in living cells and their interactions with nanomaterials.
Expertise
Microfluidics, single cell analysis, Raman spectroscopy, Raman activated cell sorting, organ-on-chip, optic imaging, optical biosensors, machine learning, system automation, surface patterning, Atomic Force Microscopy, aqueous thermal scanning microscopy.
Publications
2025
Wang, Meng ORCID: https://orcid.org/0009-0009-5148-9655, Chen, Yecang, Li, Xiaobo, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X, Paul, Manosh C.
ORCID: https://orcid.org/0000-0002-6510-456X and Dobson, Phillip S.
ORCID: https://orcid.org/0000-0001-5137-8298
(2025)
A novel CFD-DPM model for particle deposition and removal in microchannels with different contact angles.
Separation and Purification Technology, 370,
133220.
(doi: 10.1016/j.seppur.2025.133220)
Zeng, M. et al. (2025) Semipermeable membrane-mediated hydrogen bonding interface for fabricating high-performance pure PEDOT:PSS hydrogels. Advanced Materials, 37(32), 2505635. (doi: 10.1002/adma.202505635) (PMID:40394956)
Zhao, Hongyu, Mills, William, Glidle, Andrew, Liang, Peng, Li, Bei, Cooper, Jonathan M. ORCID: https://orcid.org/0000-0002-2358-1050 and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2025)
On-demand droplet formation at a T-junction: modelling and validation.
Microsystems and Nanoengineering, 11,
94.
(doi: 10.1038/s41378-025-00950-2)
(PMID:40383859)
(PMCID:PMC12086211)
Wang, Y. et al. (2025) Functionalized microwell laser sorting method for single-cell viable microbial detection. Sensors and Actuators B: Chemical, 427, 137202. (doi: 10.1016/j.snb.2024.137202)
Kaal, Joris, Feltin, Nicolas, Lelong, Marc, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Glidle, Andrew, Romieu, Kevin and Batista, Elsa
(2025)
Comparison of measurement protocols for internal channels of transparent microfluidic devices.
Metrology, 5(1),
4.
(doi: 10.3390/metrology5010004)
Li, Xiaobo, Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Glidle, Andrew, Smith, Cindy
ORCID: https://orcid.org/0000-0003-4905-0730, Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384, Cusack, Maggie and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2025)
A simple three-dimensional microfluidic platform for studying chemotaxis and cell sorting.
Lab on a Chip, 25(3),
pp. 343-353.
(doi: 10.1039/D4LC00892H)
(PMID:39758022)
2024
Zeng, M. et al. (2024) Phase separation manipulated gradient conductivity for a high-precision flexible pressure sensor. Advanced Functional Materials, 34(52), 2411390. (doi: 10.1002/adfm.202411390)
Zeng, M. et al. (2024) Dopamine-integrated all-hydrogel multi-electrode arrays for neural activity recording. Materials Horizons, 11(24), pp. 6423-6434. (doi: 10.1039/d4mh00939h) (PMID:39380329)
Luo, Yuqiu, Xua, Tiansi, Li, Bing, Liu, Fan, Wu, Beibei, Dobson, Phil S. ORCID: https://orcid.org/0000-0001-5137-8298, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X, Chen, Zheng, Qiu, Yong and Huang, Xia
(2024)
The effects of small plastic particles on antibiotic resistance gene transfer revealed by single cell and community level analysis.
Journal of Hazardous Materials, 480,
136271.
(doi: 10.1016/j.jhazmat.2024.136271)
(PMID:39515144)
Peng, Qiyun, Dong, Yingfu, Chen, Yecang, Glidle, Andrew, Kong, Lingjiang, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Xu, Jiabao
ORCID: https://orcid.org/0000-0002-1285-9408 and Yang, Kun
(2024)
Rapid profiling of fish cell nitrogen metabolism with single-cell Raman spectroscopy: unveiling enzyme’s role in ammonia detoxification.
Talanta, 277,
1216389.
(doi: 10.1016/j.talanta.2024.126389)
(PMID:38852346)
Zhang, K. et al. (2024) Investigating communication dynamics in neuronal network using 3D gold microelectrode arrays. ACS Nano, 18(26), pp. 17162-17174. (doi: 10.1021/acsnano.4c03983) (PMID:38902594)
Lee, K. S. et al. (2024) MicrobioRaman: an open-access web repository for microbiological Raman spectroscopy data. Nature Microbiology, 9, pp. 1152-1156. (doi: 10.1038/s41564-024-01656-3) (PMID:38714759)
Pu, Bin, Xiao, Gaolang, Xiao, Juying, Yin, Hua-Bing ORCID: https://orcid.org/0000-0001-7693-377X and Wang, Jin
(2024)
A strategy for improving self-healing efficiency: application of sensitizer in thymine photoresponsive materials.
Polymer, 297,
126844.
(doi: 10.1016/j.polymer.2024.126844)
Wei, Dan, Zeng, Mingze, Su, Borui, Zhang, Yusheng, Ding, Jie, Wu, Chengheng, Sun, Jing, Zhou, Liangxue, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Fan, Hongsong
(2024)
Magnetic on-off manipulated matrix mechanic vibration to enhance cell clutches-reinforcement and Ca2+ influx facilitating BMSCs neural differentiation and TBI repair.
Chemical Engineering Journal, 484,
149521.
(doi: 10.1016/j.cej.2024.149521)
Li, Bing, Mao, Siyuan, Zhang, Chi, Xu, Tiansi, Ma, Xueyan, Lin, Hai, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Qiu, Yong
(2024)
Rapid anaerobic culture and reaction kinetic study of anammox bacteria on microfluidic chip.
Bioresource Technology, 396,
130422.
(doi: 10.1016/j.biortech.2024.130422)
(PMID:38320714)
Suo, Mingqian, Fu, Yiqian, Wang, Shijia, Lin, Siqi, Zhang, Jiahui, Wu, Chunxiao, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Wang, Pu, Zhang, Wen and Wang, Xiu-Hong
(2024)
Miniaturized laser probe for exosome-based cancer liquid biopsy.
Analytical Chemistry, 96(5),
pp. 1965-1976.
(doi: 10.1021/acs.analchem.3c04187)
(PMID:38267074)
Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Yin, Jianan, Huang, Wei E., Li, Bei and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2024)
Emerging single-cell microfluidic technology for microbiology.
Trends in Analytical Chemistry, 170,
117444.
(doi: 10.1016/j.trac.2023.117444)
Peng, Qiyun, Sun, Haojie, Neilson, Lisa J., Maknitikul, Sitang, Xu, Jiabao ORCID: https://orcid.org/0000-0002-1285-9408, Kong, Lingjiang, Zanivan, Sara and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2024)
Single-Cell Analysis Reveals the Impact of Tumor-derived matrix on Cancer-Associated Fibroblasts.
In: ICBSP '24: Proceedings of the 2024 9th International Conference on Biomedical Imaging, Signal Processing, Hong Kong Shaanxi Hong Kong, 18-20 Oct 2024,
(doi: 10.1145/3707172.3707191)
2023
Li, Xiaobo, Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Chen, Xiuzhao, Yin, Jianan, Wang, Ping, Huang, He and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2023)
Single-cell microfluidics enabled dynamic evaluation of drug combinations on antibiotic resistance bacteria.
Talanta, 265,
124814.
(doi: 10.1016/j.talanta.2023.124814)
Hu, Jiaqi, Bazargan Harandi, Hesam, Chen, Yecang, Zhang, Liwei, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and He, Tao
(2023)
Anisotropic gypsum scaling of corrugated polyvinylidene fluoride hydrophobic membrane in direct contact membrane distillation.
Water Research, 244,
120513.
(doi: 10.1016/j.watres.2023.120513)
(PMID:37651864)
Yang, Y. et al. (2023) PPy/SWCNTs-modified microelectrode array for learning and memory model construction through electrical stimulation and detection of in vitro hippocampal neuronal network. ACS Applied Bio Materials, 6(9), pp. 3414-3422. (doi: 10.1021/acsabm.3c00105) (PMID:37071831)
Zhang, Y. et al. (2023) Magnetic manipulation of Fe₃O₄@BaTiO₃ nanochains to regulate extracellular topographical and electrical cues. Acta Biomaterialia, 168, pp. 470-483. (doi: 10.1016/j.actbio.2023.07.029) (PMID:37495167)
Zhang, Y. et al. (2023) Wireless-powering deep brain stimulation platform based on 1D-structured magnetoelectric nanochains applied in anti-epilepsy treatment. ACS Nano, 17(16), pp. 15796-15809. (doi: 10.1021/acsnano.3c03661)
Yang, X.‐Z. et al. (2023) A‐to‐I RNA editing in Klebsiella pneumoniae regulates quorum sensing and affects cell growth and virulence. Advanced Science, 10(17), 2206056. (doi: 10.1002/advs.202206056) (PMID:37083223) (PMCID:PMC10265045)
Xia, Zhiwen, Zhang, Xin, Yao, Jingyuan, Liu, Zihao, Jin, Yulong, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Wang, Pu and Wang, Xiu-Hong
(2023)
Giant enhancement of Raman scattering by a hollow-core microstructured optical fiber allows single exosome probing.
ACS Sensors, 8(4),
pp. 1799-1809.
(doi: 10.1021/acssensors.3c00131)
(PMID:37018734)
Xu, J. et al. (2023) Artificial intelligence-aided rapid and accurate identification of clinical fungal infections by single-cell Raman spectroscopy. Frontiers in Microbiology, 14, 1125676. (doi: 10.3389/fmicb.2023.1125676) (PMID:37032865) (PMCID:PMC10073597)
Intaravanne, Yuttana, Ansari, Muhammad Afnan, Ahmed, Hammad, Bileckaja, Narina, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Chen, Xianzhong
(2023)
Metasurface-enabled 3-in-1 microscopy.
ACS Photonics, 10(2),
pp. 544-551.
(doi: 10.1021/acsphotonics.2c01971)
Zeng, Ming-Ze, Wei, Dan, Ding, Jie, Tian, Yuan, Wu, Xiao-Yang, Chen, Zhi-Hong, Wu, Cheng-Heng, Sun, Jing, Yin, Hua-Bing ORCID: https://orcid.org/0000-0001-7693-377X and Fan, Hong-Song
(2023)
Dopamine induced multiple bonding in hyaluronic acid network to construct particle-free conductive hydrogel for reliable electro-biosensing.
Carbohydrate Polymers, 302,
120403.
(doi: 10.1016/j.carbpol.2022.120403)
(PMID:36604075)
Du, Yangkun ORCID: https://orcid.org/0000-0001-6868-4646, Stewart, Peter
ORCID: https://orcid.org/0000-0002-0971-8057, Hill, Nicholas A.
ORCID: https://orcid.org/0000-0003-3079-828X, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X, Penta, Raimondo
ORCID: https://orcid.org/0000-0003-1202-8775, Köry, Jakub
ORCID: https://orcid.org/0000-0002-4476-2547, Luo, Xiaoyu
ORCID: https://orcid.org/0000-0002-8753-4210 and Ogden, Raymond
ORCID: https://orcid.org/0000-0002-7002-7028
(2023)
Nonlinear indentation of second-order hyperelastic materials.
Journal of the Mechanics and Physics of Solids, 171,
105139.
(doi: 10.1016/j.jmps.2022.105139)
Huang, He, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Zhang, Xianzheng
(2023)
Editorial: Engineering probiotics for multiple interventions on intestinal diseases.
Frontiers in Cellular and Infection Microbiology, 13,
1138998.
(doi: 10.3389/fcimb.2023.1138998)
(PMID:36743310)
(PMCID:PMC9897589)
2022
Yin, Jianan, Chen, Xiuzhao, Li, Xiaobo, Kang, Guangbo, Wang, Ping, Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Ijaz, Umer Zeeshan
ORCID: https://orcid.org/0000-0001-5780-8551, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Huang, He
(2022)
A droplet-based microfluidic approach to isolating functional bacteria from gut microbiota.
Frontiers in Cellular and Infection Microbiology, 12,
920986.
(doi: 10.3389/fcimb.2022.920986)
Liu, Bo, Liu, Kunxiang, Wang, Nan, Ta, Kaiwen, Liang, Peng, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Li, Bei
(2022)
Laser tweezers Raman spectroscopy combined with deep learning to classify marine bacteria.
Talanta, 244,
123383.
(doi: 10.1016/j.talanta.2022.123383)
(PMID:35349842)
Blomme, A. et al. (2022) THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer. EMBO Molecular Medicine, 14(3), e14764. (doi: 10.15252/emmm.202114764) (PMID:35014179) (PMCID:PMC8899912)
Xu, Jiabao, Yi, Xiaofei, Jin, Guilan, Peng, Di, Fan, Gaoya, Xu, Xiaogang, Chen, Xin, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Cooper, Jonathan M.
ORCID: https://orcid.org/0000-0002-2358-1050 and Huang, Wei E.
(2022)
High-speed diagnosis of bacterial pathogens at the single cell level by Raman microspectroscopy with machine learning filters and denoising autoencoders.
ACS Chemical Biology, 17(2),
pp. 376-385.
(doi: 10.1021/acschembio.1c00834)
(PMID:35026119)
Liu, Li, Charlton, Laura, Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Li, Tao, Li, Xuemei, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and He, Tao
(2022)
Scaling resistance by fluoro-treatments: the importance of wetting states.
Journal of Materials Chemistry A, 10(6),
pp. 3058-3068.
(doi: 10.1039/D1TA07695G)
Liu, Yongjie, Horseman, Thomas, Wang, Zhangxin, Arafat, Hassan A., Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Lin, Shihong and He, Tao
(2022)
Negative pressure membrane distillation for excellent gypsum scaling resistance and flux enhancement.
Environmental Science and Technology, 56(2),
pp. 1405-1412.
(doi: 10.1021/acs.est.1c07144)
(PMID:34941244)
2021
He, E. et al. (2021) SWCNTs/PEDOT:PSS-modified microelectrode arrays for dual-mode detection of electrophysiological signals and dopamine concentration in the striatum under isoflurane anesthesia. ACS Sensors, 6(9), pp. 3377-3386. (doi: 10.1021/acssensors.1c01241) (PMID:34410704)
Nguyen, Anh Q., Vu, Hang P., Nguyen, Luong N., Wang, Qilin, Djordjevic, Steven P., Donner, Erica, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Nghiem, Long D.
(2021)
Monitoring antibiotic resistance genes in wastewater treatment: Current strategies and future challenges.
Science of the Total Environment, 783,
146964.
(doi: 10.1016/j.scitotenv.2021.146964)
(PMID:33866168)
Wei, Dan, Charlton, Laura, Glidle, Andrew, Qi, Nan, Dobson, Phillip S. ORCID: https://orcid.org/0000-0001-5137-8298, Dalby, Matthew John
ORCID: https://orcid.org/0000-0002-0528-3359, Fan, Hongsong and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2021)
Dynamically modulated core-shell microfibers to study the effect of depth sensing of matrix stiffness on stem cell fate.
ACS Applied Materials and Interfaces, 13(32),
pp. 37997-38006.
(doi: 10.1021/acsami.1c06752)
(PMID:34355561)
Dai, Yuchuan, Song, Yilin, Xie, Jingyu, Xu, Shengwei, Li, Xinrong, He, Enhui, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Cai, Xinxia
(2021)
In vivo microelectrode arrays for detecting multi-region epileptic activities in the hippocampus in the latent period of rat model of temporal lobe epilepsy.
Micromachines, 12(6),
659.
(doi: 10.3390/mi12060659)
Spennati, Giulia, Horowitz, Lisa F., McGarry, David J., Rudzka, Dominika A., Armstrong, Garett, Olson, Michael F., Folch, Albert and Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X
(2021)
Organotypic platform for studying cancer cell metastasis.
Experimental Cell Research, 401(2),
112527.
(doi: 10.1016/j.yexcr.2021.112527)
(PMID:33675807)
Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Glidle, Andrew, Furusho, Hitoshi and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2021)
A 3D hydrodynamic flow-focusing device for cell sorting.
Microfluidics and Nanofluidics, 25(3),
23.
(doi: 10.1007/s10404-021-02425-y)
Liu, Li, Xiao, Zechun, Liu, Yongjie, Li, Xuemei, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Volkov, Alexey and He, Tao
(2021)
Understanding the fouling/scaling resistance of superhydrophobic/omniphobic membranes in membrane distillation.
Desalination, 499,
114864.
(doi: 10.1016/j.desal.2020.114864)
2020
Lyu, Yingkai ORCID: https://orcid.org/0000-0003-0794-3792, Yuan, Xiaofei
ORCID: https://orcid.org/0000-0001-5395-9109, Glidle, Andrew, Fu, Yuchen, Furusho, Hitoshi, Yang, Tianxin and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2020)
Automated Raman based cell sorting with 3D microfluidics.
Lab on a Chip, 20(22),
pp. 4235-4245.
(doi: 10.1039/D0LC00679C)
(PMID:33057530)
Wang, Y. et al. (2020) Low sample volume origami-paper-based graphene-modified aptasensors for label-free electrochemical detection of cancer biomarker-EGFR. Microsystems and Nanoengineering, 6, 32. (doi: 10.1038/s41378-020-0146-2) (PMID:34567646) (PMCID:PMC8433370)
Liu, Yongjie, Li, Zhansheng, Xiao, Zechun, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Li, Xuemei and He, Tao
(2020)
Synergy of slippery surface and pulse flow: An anti-scaling solution for direct contact membrane distillation.
Journal of Membrane Science, 603,
118035.
(doi: 10.1016/j.memsci.2020.118035)
Liu, Yongjie, Wang, Jin, Xiao, Zechun, Liu, Li, Li, Dongdong, Li, Xuemei, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and He, Tao
(2020)
Anisotropic performance of a superhydrophobic polyvinyl difluoride membrane with corrugated pattern in direct contact membrane distillation.
Desalination, 481,
114363.
(doi: 10.1016/j.desal.2020.114363)
Xiao, Zechun, Guo, Hong, He, Hailong, Liu, Yongjie, Li, Xuemei, Zhang, Yuebiao, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Volkov, Alexey V. and He, Tao
(2020)
Unprecedented scaling/fouling resistance of omniphobic polyvinylidene fluoride membrane with silica nanoparticle coated micropillars in direct contact membrane distillation.
Journal of Membrane Science, 599,
117819.
(doi: 10.1016/j.memsci.2020.117819)
2019
Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Glidle, Andrew, Quince, Christopher, Collins, Gavin, Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384 and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2019)
Single-Cell Microfluidic Platform to Study Anaerobic Bacteria.
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019), Basel, Switzerland, 27-31 Oct 2019.
Li, Bing, Qiu, Yong, Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Lin, Hai and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2019)
Dissecting horizontal and vertical gene transfer of antibiotic resistance plasmid in bacterial community using microfluidics.
Environment International, 131,
105007.
(doi: 10.1016/j.envint.2019.105007)
(PMID:31326825)
Xiao, Zechun, Li, Zhansheng, Gou, Hong, Liu, Yongjie, Wang, Yanshai, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Li, Xuemei, Song, Jianfeng, Nghiem, Long D. and He, Tao
(2019)
Scaling mitigation in membrane distillation: from superhydrophobic to slippery.
Desalination, 466,
pp. 36-43.
(doi: 10.1016/j.desal.2019.05.006)
Keating, Ciara ORCID: https://orcid.org/0000-0001-9199-3068, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Ogundero, Ayo, Mathur, Neha
ORCID: https://orcid.org/0000-0002-2918-6908, Gonzalez-Cabaleiro, Rebeca
ORCID: https://orcid.org/0000-0002-4000-5928, Quince, Christopher, Collins, Gavin, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384
(2019)
Development of a Novel Anaerobic Incubation and Monitoring Platform Embedded with Microfluidics for Real-Time Growth Analysis of Anaerobic Cells.
The Gordon Research Seminar on Archaea: Ecology, Metabolism and Molecular Biology, Les Diablerets, Switzerland, 20-21 July 2019.
Wang, Yang, Luo, Jinping, Liu, Juntao, Sun, Shuai, Xiong, Ying, Ma, Yuanyuan, Yan, Shi, Yang, Yue, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Cai, Xinxia
(2019)
Label-free microfluidic paper-based electrochemical aptasensor for ultrasensitive and simultaneous multiplexed detection of cancer biomarkers.
Biosensors and Bioelectronics, 136,
pp. 84-90.
(doi: 10.1016/j.bios.2019.04.032)
(PMID:31039491)
Rudzka, D. A. et al. (2019) Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization. Journal of Cell Science, 132(11), jcs224071. (doi: 10.1242/jcs.224071) (PMID:31152052) (PMCID:PMC6589089)
Xiao, Z. et al. (2019) Slippery for scaling resistance in membrane distillation: a novel porous micropillared superhydrophobic surface. Water Research, 155, pp. 152-161. (doi: 10.1016/j.watres.2019.01.036) (PMID:30844676)
Keating, Ciara ORCID: https://orcid.org/0000-0001-9199-3068, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Ogundero, Ayo, Mathur, Neha
ORCID: https://orcid.org/0000-0002-2918-6908, Gonzalez-Cabaleiro, Rebeca
ORCID: https://orcid.org/0000-0002-4000-5928, Quince, Chris, Collins, Gavin, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384
(2019)
Single-Cell Real Time Analysis of the Anaerobic Bacteria Desulfovibrio Vulgaris Demonstrates Population Heterogeneity That Decreases with Increasing pH Stress [Poster].
8th Congress of European Microbiologists, Glasgow, UK, 07-11 Jul 2019.
Keating, Ciara ORCID: https://orcid.org/0000-0001-9199-3068, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Ogundero, Ayo, Mathur, Neha
ORCID: https://orcid.org/0000-0002-2918-6908, Gonzalez-Cabaleiro, Rebeca
ORCID: https://orcid.org/0000-0002-4000-5928, Quince, Chris, Collins, Gavin, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384
(2019)
Single-Cell Real Time Analysis of the Anaerobic Bacteria Desulfovibrio Vulgaris Demonstrates Population Heterogeneity That Decreases with Increasing pH Stress [Poster].
16th World Congress on Anaerobic Digestion (AD16), Delft, The Netherlands, 23-27 Jun 2019.
2018
Novo, D. et al. (2018) Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. Nature Communications, 9, 5069. (doi: 10.1038/s41467-018-07339-y) (PMID:30498210) (PMCID:PMC6265295)
Li, Bing, Qiu, Yong, Zhang, Jing, Huang, Xia, Shi, Hanchang and Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X
(2018)
Real-time study of rapid spread of antibiotic resistance plasmid in biofilm using microfluidics.
Environmental Science and Technology, 52(19),
pp. 11132-11141.
(doi: 10.1021/acs.est.8b03281)
(PMID:30179497)
Chim, Ya Hua, Mason, Louise M., Rath, Nicola, Olson, Michael F. ORCID: https://orcid.org/0000-0003-3428-3507, Tassieri, Manlio
ORCID: https://orcid.org/0000-0002-6807-0385 and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2018)
A one-step procedure to probe the viscoelastic properties of cells by Atomic Force
Microscopy.
Scientific Reports, 8,
14462.
(doi: 10.1038/s41598-018-32704-8)
(PMID:30262873)
(PMCID:PMC6160452)
Yan, Wujuan, Wang, Xiu-Hong, Yu, Jingwen, Meng, Xiaotong, Qiao, Pengfei, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Zhang, Yongzhe and Wang, Pu
(2018)
Precise and label-free tumour cell recognition based on a black phosphorus nanoquenching platform.
Journal of Materials Chemistry B, 6(35),
pp. 5613-5620.
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Yuan, X. et al. (2018) Effect of laser irradiation on cell function and its implications in Raman spectroscopy. Applied and Environmental Microbiology, 84(8), e02508-17. (doi: 10.1128/AEM.02508-17) (PMID:29427427) (PMCID:PMC5881070)
2017
Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Couto, Jillian M., Glidle, Andrew, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384 and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2017)
Single-cell microfluidics to study the effects of genome deletion on bacterial growth behavior.
ACS Synthetic Biology, 6(12),
pp. 2219-2227.
(doi: 10.1021/acssynbio.7b00177)
(PMID:28844132)
Lyu, Yingkai, Yang, Tianxin, Lu, Zhaoyu, Guo, Cheng, Ge, Chunfeng, Wang, Zhaoying, Jia, Dongfang and Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X
(2017)
External modulation method for generating accurate linear optical FMCW.
IEEE Photonics Technology Letters, 29(18),
pp. 1560-1563.
(doi: 10.1109/LPT.2017.2736561)
Wang, Jin, Yu, Xianghu, Wang, Cui, Xiang, Kechuang, Deng, Mengde and Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X
(2017)
PAMPS/MMT composite hydrogel electrolyte for solid-state supercapacitors.
Journal of Alloys and Compounds, 709,
pp. 596-601.
(doi: 10.1016/j.jallcom.2017.03.157)
Martin, Kimberly C., Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Stimac, Gregory, Bannerman, Kieran, Anderson, Jamie, Roy, Chloe, Glykofrydis, Fokion, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Davies, Jamie A.
(2017)
Symmetry-breaking in branching epithelia: cells on micro-patterns under flow challenge the hypothesis of positive feedback by a secreted autocrine inhibitor of motility.
Journal of Anatomy, 230(6),
pp. 766-774.
(doi: 10.1111/joa.12599)
(PMID:28369863)
Wei, Dan, Sun, Jing, Bolderson, Jason, Zhong, Meiling, Dalby, Matthew John ORCID: https://orcid.org/0000-0002-0528-3359, Cusack, Maggie
ORCID: https://orcid.org/0000-0003-0145-1180, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X, Fan, Hongsong and Zhang, Xingdong
(2017)
Continuous fabrication and assembly of spatial cell-laden fibers for a tissue-like construct via a photolithographic-based microfluidic chip.
ACS Applied Materials and Interfaces, 9(17),
pp. 14606-14617.
(doi: 10.1021/acsami.7b00078)
(PMID:28157291)
Hernandez-Fernaud, J. R. et al. (2017) Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nature Communications, 8, 14206. (doi: 10.1038/ncomms14206) (PMID:28198360) (PMCID:PMC5316871)
Song, Y. et al. (2017) Single-cell genomics based on Raman sorting reveals novel carotenoid-containing bacteria in the Red Sea. Microbial Biotechnology, 10(1), pp. 125-137. (doi: 10.1111/1751-7915.12420) (PMID:27748032) (PMCID:PMC5270752)
2016
Song, Yizhi, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X and Huang, Wei E.
(2016)
Raman activated cell sorting.
Current Opinion in Chemical Biology, 33,
pp. 1-8.
(doi: 10.1016/j.cbpa.2016.04.002)
(PMID:27100046)
McIlvanna, David, Huang, Wei E., Davison, Paul, Glidle, Andrew, Cooper, Jon ORCID: https://orcid.org/0000-0002-2358-1050 and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2016)
Continuous cell sorting in a flow based on single cell resonance Raman spectra.
Lab on a Chip, 16(8),
pp. 1420-1429.
(doi: 10.1039/C6LC00251J)
(PMID:26974400)
Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)
Cachat, Elise, Liu, Weijia, Martin, Kim C., Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X, Hohenstein, Peter and Davies, Jamie A.
(2016)
2- and 3-dimensional synthetic large-scale de novo patterning by mammalian cells through phase separation.
Scientific Reports, 6,
20664.
(doi: 10.1038/srep20664)
(PMID:26857385)
(PMCID:PMC4746622)
Keating, Ciara ORCID: https://orcid.org/0000-0001-9199-3068, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Quince, Chris, Collins, Gavin, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384
(2016)
Understanding Syntrophy in Anaerobic Digestion.
Brazil Newton Fund Researcher Links Workshop – Water, Sanitation, Energy Nexus, Goania, Brazil, 13-16 Sep 2016.
Li, Bing, Qiu, Yong, Shi, Hanchang and Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X
(2016)
The importance of lag time extension in determining bacterial resistance to
antibiotics.
Analyst, 141(10),
pp. 3059-3067.
(doi: 10.1039/C5AN02649K)
(PMID:27077143)
2015
Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Zhou, Mi, Gough, Julie, Glidle, Andrew and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2015)
A novel culture system for modulating single cell geometry in 3D.
Acta Biomaterialia, 24,
pp. 228-240.
(doi: 10.1016/j.actbio.2015.06.008)
(PMID:26086694)
Cameron, Jenifer M., Gabrielsen, Mads ORCID: https://orcid.org/0000-0002-9848-2276, Chim, Ya Hua, Munro, June, McGhee, Ewan J., Sumpton, David, Eaton, Philip, Anderson, Kurt I., Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Olson, Michael F.
ORCID: https://orcid.org/0000-0003-3428-3507
(2015)
Polarized cell motility induces hydrogen peroxide to inhibit cofilin via cysteine oxidation.
Current Biology, 25(11),
pp. 1520-1525.
(doi: 10.1016/j.cub.2015.04.020)
Zhou, Mi, Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Gough, Julie E.
(2015)
Restoration of chondrocytic phenotype on a two-dimensional micropatterned surface.
Biointerphases, 10,
011003.
(doi: 10.1116/1.4913565)
Zhang, Peiran, Ren, Lihui, Zhang, Xu, Shan, Yufei, Wang, Yun, Ji, Yuetong, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Huang, Wei E., Xu, Jian and Ma, Bo
(2015)
Raman-activated cell sorting based on dielectrophoretic single-cell trap and release.
Analytical Chemistry, 87(4),
pp. 2282-2289.
(doi: 10.1021/ac503974e)
(PMID:25607599)
Wang, Jin, Wu, Zongchao, Hu, Kunhong, Chen, Xiangying and Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X
(2015)
High conductivity graphene-like MoS2/polyaniline nanocomposites and its application in supercapacitor.
Journal of Alloys and Compounds, 619,
pp. 38-43.
(doi: 10.1016/j.jallcom.2014.09.008)
Hu, Zhixiong, Glidle, Andrew, Ironside, Charles, Cooper, Jonathan M. ORCID: https://orcid.org/0000-0002-2358-1050 and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2015)
An integrated microspectrometer for localised multiplexing measurements.
Lab on a Chip, 15(1),
pp. 283-289.
(doi: 10.1039/C4LC00952E)
Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Li, Bing, Qiu, Yong and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2015)
Single bacteria studies using microfluidics.
In:
Hydrocarbon and Lipid Microbiology Protocols.
Series: Springer Protocols Handbooks.
Springer.
(doi: 10.1007/8623_2015_70)
Wang, Jin, Guo, Chenchen, Yu, Yongqiang, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Liu, Xueting and Jiang, Yang
(2015)
Self-doped 3-hexylthiophene-b-sodium styrene sulfonate block copolymer: synthesis and its organization with CdSe quantum dots.
RSC Advances, 5(23),
pp. 17905-17914.
(doi: 10.1039/c4ra15195j)
2014
Li, Bing, Qiu, Yong, Glidle, Andrew, Cooper, Jon ORCID: https://orcid.org/0000-0002-2358-1050, Shi, HanChang and Yin, HuaBing
ORCID: https://orcid.org/0000-0001-7693-377X
(2014)
Single cell growth rate and morphological dynamics revealing an "opportunistic" persistence.
Analyst, 139(13),
pp. 3305-3313.
(doi: 10.1039/C4AN00170B)
Li, Bing, Qiu, Yong, Glidle, Andrew, McIlvenna, David, Luo, Qian, Cooper, Jonathan ORCID: https://orcid.org/0000-0002-2358-1050, Shi, Han-Chang and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2014)
Gradient microfluidics enables rapid bacterial growth inhibition testing.
Analytical Chemistry, 86(6),
pp. 3131-3137.
(doi: 10.1021/ac5001306)
Wang, Jing, Wu, Zongchao, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Li, Wei and Jiang, Yang
(2014)
Poly(3,4-ethylenedioxythiophene)/MoS2nanocomposites with enhanced electrochemical capacitance performance.
RSC Advances, 4(100),
pp. 56926-56932.
(doi: 10.1039/C4RA12683A)
Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Chim, Yahua and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2014)
Linking cell shape, elasticity and fate: in vitro re-differentiation of chondrocytes.
In: Optical Elastography and Tissue Biomechanics, San Francisco, CA, USA, 1-2 Feb 2014,
89460M.
(doi: 10.1117/12.2039859)
Zhao, Changwen, Lin, Zhifeng, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Ma, Yuhong, Xu, Fujian and Yang, Wantai
(2014)
PEG molecular net-cloth grafted on polymeric substrates and its bio-merits.
Scientific Reports, 4,
4982.
(doi: 10.1038/srep04982)
(PMID:24845078)
(PMCID:PMC4028697)
2013
Li, Chunyan, Glidle, Andrew, Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Hu, Zhixiong, Pulleine, Ellie, Cooper, Jon
ORCID: https://orcid.org/0000-0002-2358-1050, Yang, Wantai and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2013)
Creating “living” polymer surfaces to pattern biomolecules and cells on common plastics.
Biomacromolecules, 14(5),
pp. 1278-1286.
(doi: 10.1021/bm4000597)
(PMID:23495918)
Milton, James A., Patole, Samson, Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X, Xiao, Qiang, Brown, Tom and Melvin, Tracy
(2013)
Efficient self-assembly of DNA-functionalized fluorophores and gold nanoparticles with DNA functionalized silicon surfaces: the effect of oligomer spacers.
Nucleic Acids Research, 41(7),
e80.
(doi: 10.1093/nar/gkt031)
(PMID:23361467)
(PMCID:PMC3627567)
2012
Qiu, N. et al. (2012) Calcium carbonate microspheres as carriers for the anticancer drug camptothecin. Materials Science and Engineering C: Biomimetic and Supramolecular Systems, 32(8), pp. 2634-2640. (doi: 10.1016/j.msec.2012.08.026)
Hu, Zhixiong, Glidle, Andrew, Ironside, Charles N., Sorel, Marc ORCID: https://orcid.org/0000-0001-8365-4496, Strain, MIchael J., Cooper, Jon
ORCID: https://orcid.org/0000-0002-2358-1050 and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2012)
Integrated microspectrometer for fluorescence based analysis in a microfluidic format.
Lab on a Chip, 12(16),
pp. 2850-2857.
(doi: 10.1039/C2LC40169J)
Zarowna-Dabrowska, A. et al. (2012) Generation of primary hepatocyte microarrays by piezoelectric printing. Colloids and Surfaces B: Biointerfaces, 89, pp. 126-132. (doi: 10.1016/j.colsurfb.2011.09.016)
Cuestas-Ayllon, C., Xiao, Q., Glidle, A., Riehle, M.O. ORCID: https://orcid.org/0000-0001-7988-1514, Cooper, J.M.
ORCID: https://orcid.org/0000-0002-2358-1050, de la Fuente, J.M. and Yin, H.B.
ORCID: https://orcid.org/0000-0001-7693-377X
(2012)
A robust lithographic method for multiplex surface pattering.
Current Analytical Chemistry, 9(1),
pp. 29-36.
(doi: 10.2174/1573411011309010029)
Yin, H. ORCID: https://orcid.org/0000-0001-7693-377X and Marshall, D.
(2012)
Microfluidics for single cell analysis.
Current Opinion in Biotechnology, 23(1),
pp. 110-119.
(doi: 10.1016/j.copbio.2011.11.002)
2011
Kirchhof, K., Andar, A., Yin, H.B. ORCID: https://orcid.org/0000-0001-7693-377X, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Riehle, M.O.
ORCID: https://orcid.org/0000-0001-7988-1514 and Groth, T.
(2011)
Polyelectrolyte multilayers generated in a microfluidic device with pH gradients direct adhesion and movement of cells.
Lab on a Chip, 11(19),
pp. 3326-3335.
(doi: 10.1039/C1LC20408D)
Hu, Z., Glidle, A., Ironside, C.N., Sorel, M. ORCID: https://orcid.org/0000-0001-8365-4496, Strain, M.J. and Yin, H.
ORCID: https://orcid.org/0000-0001-7693-377X
(2011)
On-chip micro-spectrometer for fluorescence bio-sensing.
In: CLEO Europe 2011, Munich, Germany, 22-26 May 2011,
(doi: 10.1109/CLEOE.2011.5943698)
Zarowna-Dabrowska, A. et al. (2011) Miniaturized optoelectronic tweezers controlled by GaN micro-pixel light emitting diode arrays. Optics Express, 19(3), pp. 2720-2728. (doi: 10.1364/OE.19.002720)
2010
Qiu, Neng, Cai, Lu-lu, Xie, Dachun, Wang, Guangcheng, Wu, Wenshuang, Zhang, Yongkui, Song, Hang, Yin, Huabin ORCID: https://orcid.org/0000-0001-7693-377X and Chen, Lijuan
(2010)
Synthesis, structural andin vitrostudies of well-dispersed monomethoxy-poly(ethylene glycol)–honokiol conjugate micelles.
Biomedical Materials, 5(6),
065006.
(doi: 10.1088/1748-6041/5/6/065006)
(PMID:20966535)
Anderson, K.J., Cooper, J.M. ORCID: https://orcid.org/0000-0002-2358-1050, Haswell, S.J., Marshall, D., Yin, H.
ORCID: https://orcid.org/0000-0001-7693-377X and Zhang, X.L.
(2010)
Microfluidic-based measurements of cytochrome P450 enzyme activity of primary mammalian hepatocytee.
Analyst, 135(6),
pp. 1282-1287.
(doi: 10.1039/c0an00031k)
Ji, B., Cusack, M. ORCID: https://orcid.org/0000-0003-0145-1180, Freer, A., Dobson, P.S.
ORCID: https://orcid.org/0000-0001-5137-8298, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X and Yin, H.
ORCID: https://orcid.org/0000-0001-7693-377X
(2010)
Control of crystal polymorph in microfluidics using molluscan 28 kDa Ca2+-binding protein.
Integrative Biology, 2,
pp. 528-535.
(doi: 10.1039/c0ib00007h)
(PMID:20820629)
McPhee, G., Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Riehle, M.O.
ORCID: https://orcid.org/0000-0001-7988-1514 and Yin, H.
ORCID: https://orcid.org/0000-0001-7693-377X
(2010)
Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study.
Medical and Biological Engineering and Computing, 48(10),
(doi: 10.1007/s11517-010-0657-3)
Zarowna-Dabrowska, A. et al. (2010) Micromanipulation of beads and CHO cells using micro light emitting diode arrays to control a miniaturised optoelectronic tweezers device. In: IOP Photon10, Southampton, UK, 23-26 Aug 2010,
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2009
Ritchie, C., Cooper, G.J.T. ORCID: https://orcid.org/0000-0003-2341-1737, Song, Y.F., Streb, C., Yin, H.B.
ORCID: https://orcid.org/0000-0001-7693-377X, Parenty, A.D.C., MacLaren, D.A.
ORCID: https://orcid.org/0000-0003-0641-686X and Cronin, L.
ORCID: https://orcid.org/0000-0001-8035-5757
(2009)
Spontaneous assembly and real-time growth of micrometre-scale tubular structures from polyoxometalate-based inorganic solids.
Nature Chemistry, 1(1),
pp. 47-52.
(doi: 10.1038/nchem.113)
Yin, H. ORCID: https://orcid.org/0000-0001-7693-377X, Bozhi, J., Dobson, P.S.
ORCID: https://orcid.org/0000-0001-5137-8298, Mosbahi, K., Glidle, A., Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Freer, A., Cooper, J.M.
ORCID: https://orcid.org/0000-0002-2358-1050 and Cusack, M.
(2009)
Screening of biomineralization using microfluidics.
Analytical Chemistry, 81(1),
pp. 473-478.
(doi: 10.1021/ac801980b)
(PMID:19117468)
Yin, H. ORCID: https://orcid.org/0000-0001-7693-377X, McPhee, G. and Dobson, P.
ORCID: https://orcid.org/0000-0001-5137-8298
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AFM and development of (bio) fouling-resistant membranes.
In: Bowen, W.R. and Hilal, N. (eds.)
Atomic Force Microscopy in Process Engineering: Introduction to AFM for Improved Processes and Products.
Butterworth-Heinemann: Oxford, UK.
ISBN 9781856175173
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Micro/nanoengineering and AFM for cellular sensing.
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Atomic Force Microscopy in Process Engineering: Introduction to AFM for Improved Processes and Products.
Butterworth-Heinemann: Oxford, UK.
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2008
Cusack, M. ORCID: https://orcid.org/0000-0003-0145-1180, Dauphin, Y., Cuif, J.P., Salomé, M., Freer, A. and Yin, H.
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(2008)
Micro-XANES mapping of sulphur and its association with magnesium and phosphorus in the shell of the brachiopod, Terebratulina retusa.
Chemical Geology, 253(3-4),
pp. 172-179.
(doi: 10.1016/j.chemgeo.2008.05.007)
Zhang, X.L., Yin, H.B. ORCID: https://orcid.org/0000-0001-7693-377X, Cooper, J.M.
ORCID: https://orcid.org/0000-0002-2358-1050 and Haswell, S.J.
(2008)
Characterization of cellular chemical dynamics using combined microfluidic and Raman techniques.
Analytical and Bioanalytical Chemistry, 390(3),
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(doi: 10.1007/s00216-007-1564-9)
Yin, H. ORCID: https://orcid.org/0000-0001-7693-377X, Pattrick, N., Zhang, X.L., Klauke, N., Cordingley, H.C., Haswell, S.J. and Cooper, J.M.
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Quantitative comparison between microfluidic and microtiter plate formats for cell-based assays.
Analytical Chemistry, 80(1),
pp. 179-185.
(doi: 10.1021/ac701958z)
Mushfique, H., Leach, J., Yin, H. ORCID: https://orcid.org/0000-0001-7693-377X, Di Leonardo, R., Padgett, M.J.
ORCID: https://orcid.org/0000-0001-6643-0618 and Cooper, J.M.
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Book Sections
Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Li, Bing, Qiu, Yong and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
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In:
Hydrocarbon and Lipid Microbiology Protocols.
Series: Springer Protocols Handbooks.
Springer.
(doi: 10.1007/8623_2015_70)
Yin, H. ORCID: https://orcid.org/0000-0001-7693-377X, McPhee, G. and Dobson, P.
ORCID: https://orcid.org/0000-0001-5137-8298
(2009)
AFM and development of (bio) fouling-resistant membranes.
In: Bowen, W.R. and Hilal, N. (eds.)
Atomic Force Microscopy in Process Engineering: Introduction to AFM for Improved Processes and Products.
Butterworth-Heinemann: Oxford, UK.
ISBN 9781856175173
Yin, H. ORCID: https://orcid.org/0000-0001-7693-377X, McPhee, G. and Dobson, P.
ORCID: https://orcid.org/0000-0001-5137-8298
(2009)
Micro/nanoengineering and AFM for cellular sensing.
In: Bowen, W.R. and Hilal, N. (eds.)
Atomic Force Microscopy in Process Engineering: Introduction to AFM for Improved Processes and Products.
Butterworth-Heinemann: Oxford, UK.
ISBN 9781856175173
Conference or Workshop Item
Song, Yanqing ORCID: https://orcid.org/0000-0002-8338-4016, Glidle, Andrew, Quince, Christopher, Collins, Gavin, Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384 and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2019)
Single-Cell Microfluidic Platform to Study Anaerobic Bacteria.
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019), Basel, Switzerland, 27-31 Oct 2019.
Keating, Ciara ORCID: https://orcid.org/0000-0001-9199-3068, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Ogundero, Ayo, Mathur, Neha
ORCID: https://orcid.org/0000-0002-2918-6908, Gonzalez-Cabaleiro, Rebeca
ORCID: https://orcid.org/0000-0002-4000-5928, Quince, Christopher, Collins, Gavin, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384
(2019)
Development of a Novel Anaerobic Incubation and Monitoring Platform Embedded with Microfluidics for Real-Time Growth Analysis of Anaerobic Cells.
The Gordon Research Seminar on Archaea: Ecology, Metabolism and Molecular Biology, Les Diablerets, Switzerland, 20-21 July 2019.
Keating, Ciara ORCID: https://orcid.org/0000-0001-9199-3068, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Ogundero, Ayo, Mathur, Neha
ORCID: https://orcid.org/0000-0002-2918-6908, Gonzalez-Cabaleiro, Rebeca
ORCID: https://orcid.org/0000-0002-4000-5928, Quince, Chris, Collins, Gavin, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384
(2019)
Single-Cell Real Time Analysis of the Anaerobic Bacteria Desulfovibrio Vulgaris Demonstrates Population Heterogeneity That Decreases with Increasing pH Stress [Poster].
8th Congress of European Microbiologists, Glasgow, UK, 07-11 Jul 2019.
Keating, Ciara ORCID: https://orcid.org/0000-0001-9199-3068, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Ogundero, Ayo, Mathur, Neha
ORCID: https://orcid.org/0000-0002-2918-6908, Gonzalez-Cabaleiro, Rebeca
ORCID: https://orcid.org/0000-0002-4000-5928, Quince, Chris, Collins, Gavin, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384
(2019)
Single-Cell Real Time Analysis of the Anaerobic Bacteria Desulfovibrio Vulgaris Demonstrates Population Heterogeneity That Decreases with Increasing pH Stress [Poster].
16th World Congress on Anaerobic Digestion (AD16), Delft, The Netherlands, 23-27 Jun 2019.
Keating, Ciara ORCID: https://orcid.org/0000-0001-9199-3068, Song, Yanqing
ORCID: https://orcid.org/0000-0002-8338-4016, Quince, Chris, Collins, Gavin, Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X and Sloan, William
ORCID: https://orcid.org/0000-0002-9450-7384
(2016)
Understanding Syntrophy in Anaerobic Digestion.
Brazil Newton Fund Researcher Links Workshop – Water, Sanitation, Energy Nexus, Goania, Brazil, 13-16 Sep 2016.
Conference Proceedings
Peng, Qiyun, Sun, Haojie, Neilson, Lisa J., Maknitikul, Sitang, Xu, Jiabao ORCID: https://orcid.org/0000-0002-1285-9408, Kong, Lingjiang, Zanivan, Sara and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2024)
Single-Cell Analysis Reveals the Impact of Tumor-derived matrix on Cancer-Associated Fibroblasts.
In: ICBSP '24: Proceedings of the 2024 9th International Conference on Biomedical Imaging, Signal Processing, Hong Kong Shaanxi Hong Kong, 18-20 Oct 2024,
(doi: 10.1145/3707172.3707191)
Yuan, Xiaofei ORCID: https://orcid.org/0000-0001-5395-9109, Chim, Yahua and Yin, Huabing
ORCID: https://orcid.org/0000-0001-7693-377X
(2014)
Linking cell shape, elasticity and fate: in vitro re-differentiation of chondrocytes.
In: Optical Elastography and Tissue Biomechanics, San Francisco, CA, USA, 1-2 Feb 2014,
89460M.
(doi: 10.1117/12.2039859)
Hu, Z., Glidle, A., Ironside, C.N., Sorel, M. ORCID: https://orcid.org/0000-0001-8365-4496, Strain, M.J. and Yin, H.
ORCID: https://orcid.org/0000-0001-7693-377X
(2011)
On-chip micro-spectrometer for fluorescence bio-sensing.
In: CLEO Europe 2011, Munich, Germany, 22-26 May 2011,
(doi: 10.1109/CLEOE.2011.5943698)
Zarowna-Dabrowska, A. et al. (2010) Micromanipulation of beads and CHO cells using micro light emitting diode arrays to control a miniaturised optoelectronic tweezers device. In: IOP Photon10, Southampton, UK, 23-26 Aug 2010,
Zarowna-Dabrowska, A. et al. (2010) Miniaturised optoelectronic tweezers controlled by GaN micro light emitting diode arrays. In: 23rd Annual Meeting of the IEEE Photonics Society, Denver, CO, 7-11 Nov 2010,
Melvin, T. et al. (2006) DNA, Nanoparticles and Photons - New Approaches for Clinical Diagnostics. In: 2006 International Symposium on Biophotonics, Nanophotonics and Metamaterials, Hangzhou, China, 16-18 Oct 2006, pp. 20-21. ISBN 9780780397743 (doi: 10.1109/METAMAT.2006.334986)
Yin, Huabing B. ORCID: https://orcid.org/0000-0001-7693-377X, Brown, Tom, Greef, Robert, Mailis, Sakellaris, Eason, Rob, Wilkinson, James S. and Melvin, Tracy
(2004)
Photopatterning of DNA oligonucleotides on silicon surfaces with micron-scale dimensions.
In: Biophotonics New Frontier: From Genome to Proteome, Strasbourg, France, 26 Apr 2004,
ISBN 9780819453846
(doi: 10.1117/12.545736)
Grants
- 2025-2027: High resolution molecular profiling platform to Investigate the role of tumour microbiota in anti-tumour immunity. MRC, PI.
- 2025-2027: UK-Japan collaboration for artificial photosynthetic systems. BBSRC, Co-I
- 2023-2024: Clinical validation and exploitation for rapid pathogen diagnosis platforms. ESPRC, PI.
- 2022-2026: The Blueprint for Marine Biomineralization in a Changing Climate. NERC, Co-I.
- 2022-2024: Establish flow-based Raman activated sorting platform. Industry, PI.
- 2020-2021: A gut microbiota chip for functional analysis of herbal medicine. EPSRC, PI.
- 2019-2024: An integrated microfluidic – single cell Raman technology for rapid diagnosis of pathogens and their antibiotic resistance. InnovateUK, PI.
- 2020-2025: SofTMech with MIT and POLIMI. EPSRC, Co-I.
- 2019-2027: EPSRC and SFI Centre for Doctoral Training in Engineered Tissues for Discovery, Industry and Medicine. EPSRC, Co-I.
- 2018-2022: LinkPI: Linking Phenotype function with Identity: a novel integrated single-cell technology and metagenomics approach. NERC, PI.
- 2018-2020: An Aqueous Scanning Thermal Microscope for nanoscale thermal biology. BBSRC, Co-I.
- 2017-2021: Nanotechnology for clean water: High throughput, In-situ analysis of biofouling in membrane separation processes. Royal Society (Newton Advanced Fellowship).
- 2017-2021: When Isotopes don’t clump….. NERC, Co-I.
- 2016-2017: Stable Isotope Probing with Resonance Raman Cell Sorting to profile influence of ocean acidification on microbial carbon fixation. NERC, PI.
- 2016-2018: Engineering Microbial Cell Factories for Industrial Carotenoids Biosynthesis. IBioIC, PI.
- 2016-2020: EPSRC Centre for Multiscale Soft Tissue Mechanics - with application to heart & cancer. EPSRC, Co-I.
- 2014-2019: Development of a continuous microfluidic – Raman sorting platform. NISSAN-CHEM Ltd, PI.
- 2013-2014: Microfluidic fibre extrusion for bone replacement. BBSRC, Co-I.
- 2012-2014: Shell inspiration: turning nature’s secrets into engineering solutions. EPSRC, PI.
- 2012-2013: Generation of a large family of genetic logic gates for applications in biosensing and information processing. BBSRC, Co-I.
- 2010-2016: Engineering a semi-biotic immune system. EPSRC, Co-I.
- 2010-2014: Delivery of cell phenotype authentication. EPSRC & LGC Ltd Case award.
- 2010-2012: Substrate control of cell shape and effect on gene expression”, in collaboration with the University of Manchester. The Leverhulme Trust.
- 2010-2012: Collagen characterization. KTP and Devro plc, PI.
- 2010-2011: Microfluidic technology for controlled synthesis of nanodelivery systems. Royal Academy of Engineering, PI.
- 2006-2009: Click-Chemistries for 2D and 3D Programmable Surfaces. Royal Society of Edinburgh Personal Research Fellowship.
Supervision
Research Associates (Current)
Dr Mohammadrahim Kazemzadeh
William Mills
PhD students (as 1st supervisor)
Qiyun Peng
Shuai Pu
Sitang Maknitikul
Xiaobo Li
Owen Drabwell
Carlie Rein
Ollie Whitley
- Drabwell, Owen
Automated cell sorting platforms using Al-assisted Raman spectroscopy - Kyle, Aodhan
Nano-scale measurement and manipulation of heat for healthcare. - Li, Sixuan
Advanced nanoscale thermal and biomechanical technologies for cancer research. - Maknitikul, Sitang
Investigating the cancer metabolites influence tumour microenvironment to promote cancer dissemination - Moore, Luke
Capturing Low Abundance but Highly Active Nitrifiers
Teaching
- Microscopy and Optics III (ENG3038) - Course coordinator
- Engineering in Biology (ENG2087)
- Biomaterials II (ENG2011) - Course coordinator
Additional information
Potential PhD Projects
My group is a multidisciplinary team of engineers, chemists, biologists, and computer scientists. We welcome motivated researchers with interests in artificial intelligence, microfluidics, automation, and clinical or environmental applications. If you are interested, please contact me at huabing.yin@glasgow.ac.uk with your CV. I will support you in applying for relevant scholarships.
Rapid Diagnosis of Infectious Diseases and Antimicrobial Resistance
Antimicrobial resistance (AMR) has become one of the most significant threats to global health. Rapid diagnosis of infectious diseases is crucial to combating AMR, especially in life-threatening conditions such as sepsis. We have recently developed a transformative microfluidic–Raman spectroscopy platform that enables rapid, sample-to-result diagnosis within 20 minutes [1]. This project focuses on translating this platform technology into real-world diagnostic workflows in collaboration with our hospital and industry partners. It offers an excellent opportunity for a student with a background in microbiology to harness advances in artificial intelligence, imaging, and engineering to address pressing global challenges.
[1] Li, Y., Xu, J., Yi, X. et al. Rapid culture-free diagnosis of clinical pathogens via integrated microfluidic-Raman micro-spectroscopy. Nat Commun (2025). https://doi.org/10.1038/s41467-025-66996-y
Automated Biolab-on-a-Chip
As societies face growing challenges in health and sustainability, the ability to create new biological systems is becoming increasingly important. This project aims to design and build an automated biolab-on-a-chip platform that integrates microfluidics, sensing, robotics, and AI-driven control to accelerate biological experimentation. The system will automate the full design–build–test–learn cycle for engineering bacteria with new functions, such as converting CO₂ into valuable products.
The project will leverage state-of-the-art microfluidic technologies in Professor Yin’s lab, including integrated microfluidic platforms with real-time sensing, machine-learning-enabled automation, and close-loop control. The PhD candidate will be embedded within a highly interdisciplinary consortium and work closely with synthetic biologists to translate de novo AI designs into functional biological systems addressing real-world challenges. The student will also join an exchange programme for early career researchers from the University of Tokyo, University of Oxford, University of Glasgow, University of Southampton, University of Birmingham, and University of Cambridge, supported by the UK-Japan Engineering Biology Scheme.
AI-driven signal and imaging analysis in cancer diagnosis
Cancer remains one of the leading causes of death worldwide. Increasing evidence indicates that how cancers develop and respond to treatments is linked to each patient’s unique tumour microenvironment. A deeper understanding of the roles the tumour microenvironment plays in cancer development could lead to improved early diagnosis and the development of more precisely-targeted and effective therapies.
The aim of this PhD project is to leverage cutting-edge Raman spectroscopy, combined with AI-driven image analysis and bioinformatics tools, to map molecular information in clinical tissue samples. This approach will provide a holistic view of the cancer cell biology, offering the potential to identify biomarkers for early diagnosis and to stratify patients for tailored treatment regimens. The project is a part of international collaboration, and the student will join a dynamic, interdisciplinary team, working alongside world-class research groups at the University of Oxford, National Physical Laboratory, London and MD Anderson Cancer Centre, Texas.
